Funny thing is that only two main cast members are below the age of 25. Most are aged 30-40. The coolest thing is that some of the actors from the movies are the voices of their characters in the cartoon (J. Jonah Jameson and Agent Coulson). That, and that SpongeBob is Doc Octopus.
CAST:
Drake Bell – Peter Parker / Spider-Man,[1][25][26] Swarm (2nd appearance)
Ogie Banks – Luke Cage / Power Man[27]
Greg Cipes – Danny Rand / Iron Fist[27]
Clark Gregg – Phil Coulson[25]
Tom Kenny – Dr. Otto Octavius / Doctor Octopus,[28] Bentley Whittman / Wizard,[29] David Cannon / Whirlwind,[30] Dr. Curt Connors (first few episodes),[31] Aries Zodiac Soldier,[32] Adrian Toomes / Vulture
Matt Lanter – Harry Osborn,[27] Flash Thompson/Agent Venom,[27] Venom,[33] Ulysses Klaw / Klaw[29]
Misty Lee – May Reilly-Parker,[27] Salem's Witch,[34] Doreen Green/Squirrel Girl
Caitlyn Taylor Love – Ava Ayala / White Tiger[27]
Chi McBride – Nick Fury,[25][35] Eiliot Franklin / Thunderball,[36] Taurus Zodiac Soldier[37]
Logan Miller – Sam Alexander / Nova[27]
J. K. Simmons – J. Jonah Jameson[7]
Tara Strong – Mary Jane Watson,[27] Thundra,[29] Sandy
Steven Weber – Norman Osborn / Green Goblin / Goblin-Venom / Iron Patriot,[25][27] Peter Petruski / Trapster[29]